Blood samples were collected at regular intervals.
Theracurmin containing 90 mg of curcumin.
Verbal performance buschke selective reminding test srt visual performance brief visual memory test revised bvmt r.
The intervention is twice daily dosage of theracurmin 90 mg capsules.
Individuals were asked not to consume curcumin containing food for more than 7 days prior to the study.
Subjects will be randomly assigned to one of two treatment groups.
The study lasted for 3 weeks.
The experimental group took theracurmin containing 90 mg of curcumin twice daily i e 180 mg curcumin day for 18 months.
6 capsules equivalent to 180 mg curcumin.
Bioavailable curcumin normal aging memory cognition positron emission tomography highlights this is the first long term 18 months double blind placebo controlled trial of a bioavailable form of curcumin theracurmin containing 90 mg of curcumin twice daily in non demented adults.
Attention was assessed as a secondary outcome.
1 capsule equivalent to 260 mg.
Forty subjects age 51 84 years were randomized to a bioavailable form of curcumin theracurmin containing 90 mg of curcumin twice daily n 21 or placebo n 19 for 18 months.
The dosage of curcumin from each supplement type was not equal.
Theracurmin is a novel preparation of turmeric that utilizes patented colloidal dispersion technology to enhance bioavailability and dramatically increase curcumin levels in the blood unlike other forms of curcumin theracurmin is water dispersible meaning it dissolves quickly and maintains solubility over time thereby improving curcumin s overall absorption.
The following tests were used to assess cognitive performance.
Microcrystalline cellulose vegetable capsule carbohydrate gum cellulose purified water magnesium stearate vegetable grade silica.
Theracurmin hp capsules containing 90 mg curcumin each that will be taken as one capsule twice daily for 6 months.
This same dose was used in a successful trial of patients with mild cognitive impairment.
30 mg providing a controlled surface the colloidal dispersion 30 mg of curcumin turmeric root extract daily value not established other ingredients.
Primary outcomes were verbal buschke selective reminding test srt and visual brief visual memory test revised bvmt r memory and attention trail making a was a secondary outcome.
The experimental group took theracurmin containing 90 mg of curcumin twice a day ie 180 mg curcumin day for 18 months.